Name: TBXAS1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： TBXAS1抗原（重組蛋白）

英文名稱： TBXAS1 Antigen (Recombinant Protein)

別名： TS; TXS; CYP5; THAS; TXAS; CYP5A1; GHOSAL; BDPLT14

儲存： 冷凍（-20℃）

相關類別： 抗原

概述：

Fusion protein corresponding to a region derived from C terminal 250 amino acids of human TBXAS1

技術規格：

Full name:	thromboxane A synthase 1 (platelet)
Synonyms:	TS; TXS; CYP5; THAS; TXAS; CYP5A1; GHOSAL; BDPLT14
Swissprot:	P24557
Gene Accession:	BC014117
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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