Name: KLF17抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：KLF17抗原（重組蛋白）

英文名稱： KLF17 Antigen (Recombinant Protein)

別名：ZNF393; Zfp393; RP4-675G8.1

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to C terminal 250 amino acids of human KLF17

技術(shù)規(guī)格：

Full name:	Kruppel-like factor 17
Synonyms:	ZNF393; Zfp393; RP4-675G8.1
Swissprot:	Q5JT82
Gene Accession:	BC049844
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Krueppel-like factor 17 is a protein that in humans is encoded by the KLF17 gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

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