Name: ACAD11 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：ACAD11 抗原（重組蛋白）

英文名稱： ACAD11 Antigen (Recombinant Protein)

別名： Acyl-CoA dehydrogenase family, member 11; ACAD-11

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 121-400 amino acids of human ACAD11

技術(shù)規(guī)格：

Full name:	Acyl-CoA dehydrogenase family, member 11
Synonyms:	ACAD-11
Swissprot:	Q709F0
Gene Accession:	BC125204
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The deduced full-length ACAD11 protein contains an N-terminal aminoglycoside phosphotransferase domain, followed by a mitochondria localization signal and ACAD N-terminal, middle, and C-terminal domains. It also has a glycosylation site and a C-terminal peroxisome-targeting signal. The ACAD domain contains a catalytic aspartate rather than the catalytic glutamate found in most other ACADs. Real-time RT-PCR detected variable ACAD11 expression in all tissues examined, with highest expression in adult brain, followed by heart, liver, spinal cord, and kidney. Western blot analysis of fractionated human cerebellum and kidney revealed thatACAD11 associated with mitochondrial membranes, but not mitochondrial matrix. Immunohistochemical analysis showed that ACAD11colocalized with a mitochondrial marker in human neuroblastoma cells.

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