Name: COL9A1 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： COL9A1 抗原（重組蛋白）

英文名稱： COL9A1 Antigen (Recombinant Protein)

別名： collagen type IX alpha 1 chain; MED; EDM6; STL4; DJ149L1.1.2

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 24-328 amino acids of human COL9A1

技術(shù)規(guī)格

Full name:	collagen type IX alpha 1 chain
Synonyms:	MED; EDM6; STL4; DJ149L1.1.2
Swissprot:	P20849
Gene Accession:	BC015409
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.

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