中文名稱：GCNT2 抗原（重組蛋白）

英文名稱：GCNT2 Antigen (Recombinant Protein)

別名：glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group); II; CCAT; IGNT; ULG3; GCNT5; GCNT2C; NACGT1; NAGCT1; CTRC

相關(guān)類別：抗原

儲(chǔ) 存：冷凍（-20℃）

概述

Fusion protein corresponding to a region derived from 203-402 amino acids of human GCNT2

技術(shù)規(guī)格

Full name:

glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)

Synonyms:

II; CCAT; IGNT; ULG3; GCNT5; GCNT2C; NACGT1; NAGCT1; CTRCT13; bA421M1.1; bA360O19.2

Swissprot:

Q8N0V5

Gene Accession:

BC130524

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.

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GCNT2抗原（重組蛋白）說(shuō)明書
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GCNT2抗原（重組蛋白）

Full name:	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
Synonyms:	II; CCAT; IGNT; ULG3; GCNT5; GCNT2C; NACGT1; NAGCT1; CTRCT13; bA421M1.1; bA360O19.2
Swissprot:	Q8N0V5
Gene Accession:	BC130524
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.