中文名稱： GCLC 抗原（重組蛋白）

英文名稱：GCLC Antigen (Recombinant Protein)

別名：glutamate-cysteine ligase, catalytic subunit; GCL; GCS; GLCL; GLCLC

相關類別：抗原

儲存：冷凍（-20℃）

概述

Fusion protein corresponding to N terminal 252 amino acids of human GCLC

技術規格

Full name:

glutamate-cysteine ligase, catalytic subunit

Synonyms:

GCL; GCS; GLCL; GLCLC

Swissprot:

P48506

Gene Accession:

BC022487

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.

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細胞庫

基礎培養基

完全培養基

原代細胞

細胞專用培養基

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GCLC抗原（重組蛋白）

Full name:	glutamate-cysteine ligase, catalytic subunit
Synonyms:	GCL; GCS; GLCL; GLCLC
Swissprot:	P48506
Gene Accession:	BC022487
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.