購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. |
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Applications: |
ELISA, WB |
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Name of antibody: |
KBTBD8 |
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Immunogen: |
Fusion protein of human KBTBD8 |
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Full name: |
kelch repeat and BTB domain containing 8 |
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Synonyms: |
TAKRP; TA-KRP |
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SwissProt: |
Q8NFY9 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
69 kDa |
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WB Positive control: |
NIH/3T3 cell lysate |
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WB Recommended dilution: |
1000-5000 |
