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021-54845833/15800441009
中文名稱： 兔抗PRKACA(Phospho-Thr197) 多克隆抗體
英文名稱： Anti-PRKACA(Phospho-Thr197) rabbit polyclonal antibody
別 名： PKACA
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： PRKACA(Phospho-Thr197)
反應(yīng)種屬： Human Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
PRKACA(Phospho-Thr197) |
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Immunogen: |
Peptide sequence around phosphorylation site of threonine 197(R-T-W(p)-T-L) derived from Human PKA α/β CAT. |
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Full name: |
protein kinase, cAMP-dependent, catalytic, alpha |
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Synonyms： |
PKACA |
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SwissProt: |
P17612 |
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IHC positive control: |
Human colon carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
41 kDa |
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WB Positive control: |
Mouse brain tissue lysates |
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WB Recommended dilution: |
500-1000 |
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IF positive control: |
A549 cells |
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IF Recommend dilution: |
100-200 |
