購物車
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021-54845833/15800441009
中文名稱：AAK1抗原（重組蛋白）
英文名稱： AAK1 Antigen (Recombinant Protein)
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概述
Fusion protein corresponding to N terminal 236 amino acids of human AAK1
Full name:
AP2 associated kinase 1
Swissprot:
Q2M2I8
Gene Accession:
BC002695
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
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