購物車
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021-54845833/15800441009
英文名稱： Anti-HUWE1 rabbit polyclonal antibody
反應種屬： Human, Mouse, Rat
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術規格
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Background: |
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
HUWE1 |
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Immunogen: |
Synthetic peptide of human HUWE1 |
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Full name: |
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
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Synonyms: |
MULE; Ib772; LASU1; UREB1; HECTH9; URE-B1; ARF-BP1; HSPC272 |
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SwissProt: |
Q7Z6Z7 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human esophagus cancer and human lung cancer |
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IHC Recommend dilution: |
10-50 |
