中文名稱：小鼠抗AMDHD1單克隆抗體

英文名稱： Anti-AMDHD1 mouse monoclonal antibody

別名： amidohydrolase domain containing 1; HMFT1272

相關(guān)類別：一抗

儲(chǔ) 存： 冷凍（-20℃）

宿主： Mouse

抗原： AMDHD1

反應(yīng)種屬： Human

標(biāo) 記物： Unconjugate

克隆類型： mouse monoclonal

技術(shù)規(guī)格

Background:

AMDHD1 (amidohydrolase domain containing 1), also known as probable imidazolonepropionase, is a 426 amino acid protein belonging to the hutI family. AMDHD1 participates in hydrolase activity, acting on carbon-nitrogen bonds, but not peptide bonds, in cyclic amides. AMDHD1 also functions in imidazolonepropionase activity and metal ion binding, whereby binding one iron or zinc ion per subunit. AMDHD1 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes within 132 million bases and makes up approximately 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, characterized by heart and facial developmental defects, is caused by a mutant form of the PTPN11 gene product, SH-PTP2. Chromosome 12 is also linked to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster that encodes C-type lectin proteins, which mediate the NK cell response to MHC I interaction.

Applications:

WB, IHC

Name of antibody:

AMDHD1

Immunogen:

Fusion protein of human AMDHD1

Full name:

amidohydrolase domain containing 1

Synonyms:

HMFT1272

SwissProt:

Q96NU7

IHC positive control:

Human pancreas tissue

IHC Recommend dilution:

200-500

WB Predicted band size:

47 KD

WB Positive control:

Human liver tissue lysates

WB Recommended dilution:

200-1000

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小鼠抗AMDHD1單克隆抗體

Background:	AMDHD1 (amidohydrolase domain containing 1), also known as probable imidazolonepropionase, is a 426 amino acid protein belonging to the hutI family. AMDHD1 participates in hydrolase activity, acting on carbon-nitrogen bonds, but not peptide bonds, in cyclic amides. AMDHD1 also functions in imidazolonepropionase activity and metal ion binding, whereby binding one iron or zinc ion per subunit. AMDHD1 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes within 132 million bases and makes up approximately 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, characterized by heart and facial developmental defects, is caused by a mutant form of the PTPN11 gene product, SH-PTP2. Chromosome 12 is also linked to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster that encodes C-type lectin proteins, which mediate the NK cell response to MHC I interaction.
Applications:	WB, IHC
Name of antibody:	AMDHD1
Immunogen:	Fusion protein of human AMDHD1
Full name:	amidohydrolase domain containing 1
Synonyms:	HMFT1272
SwissProt:	Q96NU7
IHC positive control:	Human pancreas tissue
IHC Recommend dilution:	200-500
WB Predicted band size:	47 KD
WB Positive control:	Human liver tissue lysates
WB Recommended dilution:	200-1000