Name: RNF128 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： RNF128 抗原（重組蛋白）

英文名稱： RNF128 Antigen (Recombinant Protein)

別名： ring finger protein 128; GRAIL

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from 39-207 amino acids of human RNF128

技術規格

Full name:	ring finger protein 128
Synonyms:	GRAIL
Swissprot:	Q8TEB7
Gene Accession:	BC063404
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

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