中文名稱：兔抗TCF3(Phospho-Thr355) 多克隆抗體

英文名稱： Anti-TCF3(Phospho-Thr355) rabbit polyclonal antibody

別名： E2A; E47; ITF1; VDIR; TCF-3; bHLHb21

相關(guān)類別：一抗

儲(chǔ) 存： 冷凍（-20℃）避光

宿主： Rabbit

抗原： TCF3(Phospho-Thr355)

反應(yīng)種屬： Human Mouse Rat

標(biāo) 記物： Unconjugate

克隆類型： Unconjugate

技術(shù)規(guī)格

Background:

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]

Applications:

IHC

Name of antibody:

TCF3(Phospho-Thr355)

Immunogen:

Peptide sequence around phosphorylation site of threonine 355 (P-S-T(p)-P-V) derived from Human E2A .

Full name:

transcription factor 3

Synonyms：

E2A; E47; ITF1; VDIR; TCF-3; bHLHb21

SwissProt:

P15923

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

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兔抗TCF3(Phospho-Thr355) 多克隆抗體

Background:	This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]
Applications:	IHC
Name of antibody:	TCF3(Phospho-Thr355)
Immunogen:	Peptide sequence around phosphorylation site of threonine 355 (P-S-T(p)-P-V) derived from Human E2A .
Full name:	transcription factor 3
Synonyms：	E2A; E47; ITF1; VDIR; TCF-3; bHLHb21
SwissProt:	P15923
IHC positive control:	Human brain tissue
IHC Recommend dilution:	50-100