中文名稱：兔抗SP1 (Phospho-Thr739)多克隆抗體

英文名稱： Anti-SP1 (Phospho-Thr739) rabbit polyclonal antibody

相關(guān)類別：一抗

儲(chǔ) 存： 冷凍（-20℃）避光

宿主： Rabbit

抗原： SP1 (Phospho-Thr739)

反應(yīng)種屬： Human Mouse Rat

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

Applications:

WB

Name of antibody:

SP1 (Phospho-Thr739)

Immunogen:

Synthetic peptide of human SP1 (Phospho-Thr739)

Full name:

Sp1 transcription factor (Phospho-Thr739)

SwissProt:

P08047

WB Predicted band size:

81 kDa

WB Positive control:

NIH/3T3 cells treated with serum starvation

WB Recommended dilution:

500-1000

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兔抗SP1 (Phospho-Thr739)多克隆抗體

Background:	Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Applications:	WB
Name of antibody:	SP1 (Phospho-Thr739)
Immunogen:	Synthetic peptide of human SP1 (Phospho-Thr739)
Full name:	Sp1 transcription factor (Phospho-Thr739)
SwissProt:	P08047
WB Predicted band size:	81 kDa
WB Positive control:	NIH/3T3 cells treated with serum starvation
WB Recommended dilution:	500-1000