Background: |
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. |
Applications: |
IHC, IF |
Name of antibody: |
GRIN1(Phospho-Ser890) |
Immunogen: |
Peptide sequence around phosphorylation site of Serine 890(A-S-S(p)-F-K) derived from Human NMDAR1. |
Full name: |
glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
Synonyms: |
NR1; MRD8; GluN1; NMDA1; NMDAR1 |
SwissProt: |
Q05586 |
IHC positive control: |
Human brain tissue |
IHC Recommend dilution: |
50-100 |
IF positive control: |
A549 cells |
IF Recommend dilution: |
100-200 |

