中文名稱：兔抗GRID2多克隆抗體

英文名稱： Anti-GRID2 rabbit polyclonal antibody

別名： GluD2

抗原： GRID2

儲存： 冷凍（-20℃）避光

宿主： Rabbit

反應種屬： Human Mouse Rat

相關類別：一抗

標記物： Unconjugate

克隆類型： Unconjugate

技術規格

Background:

The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans.

Applications:

WB, IF

Name of antibody:

GRID2

Immunogen:

Synthesized peptide derived from internal of human GRID2.

Full name:

glutamate receptor, ionotropic, delta 2

Synonyms：

GluD2

SwissProt:

O43424

WB Predicted band size:

113 kDa

WB Positive control:

NIH/3T3 cells lysate

WB Recommended dilution:

500-3000

IF positive control:

Huvec cells

IF Recommend dilution:

100-500

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兔抗GRID2多克隆抗體說明書
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兔抗GRID2多克隆抗體

Background:	The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans.
Applications:	WB, IF
Name of antibody:	GRID2
Immunogen:	Synthesized peptide derived from internal of human GRID2.
Full name:	glutamate receptor, ionotropic, delta 2
Synonyms：	GluD2
SwissProt:	O43424
WB Predicted band size:	113 kDa
WB Positive control:	NIH/3T3 cells lysate
WB Recommended dilution:	500-3000
IF positive control:	Huvec cells
IF Recommend dilution:	100-500