Background: |
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
FCAR |
Immunogen: |
Fusion protein of human FCAR |
Full name: |
Immunoglobulin alpha Fc receptor |
Synonyms: |
CD89 |
SwissProt: |
P24071 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer and Human prostate cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
32 kDa |
WB Positive control: |
293T cells |
WB Recommended dilution: |
500-2000 |
