中文名稱：兔抗ERBB2(Phospho-Tyr1112) 多克隆抗體

英文名稱： Anti-ERBB2(Phospho-Tyr1112) rabbit polyclonal antibody

別名： NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu

相關類別： 一抗

儲存： 冷凍（-20℃）避光

宿主： Rabbit

抗原： ERBB2(Phospho-Tyr1112)

反應種屬： Human

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術規格

Background:

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here.

Applications:

WB

Name of antibody:

ERBB2(Phospho-Tyr1112)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 1112 (Q-R-Y(p)-S-E) derived from Human HER2.

Full name:

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2

Synonyms：

NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu

SwissProt:

P04626

WB Predicted band size:

138 kDa

WB Positive control:

HepG2 cells lysates

WB Recommended dilution:

500-1000

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兔抗ERBB2(Phospho-Tyr1112) 多克隆抗體說明書
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兔抗ERBB2(Phospho-Tyr1112) 多克隆抗體

Background:	This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here.
Applications:	WB
Name of antibody:	ERBB2(Phospho-Tyr1112)
Immunogen:	Peptide sequence around phosphorylation site of tyrosine 1112 (Q-R-Y(p)-S-E) derived from Human HER2.
Full name:	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
Synonyms：	NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu
SwissProt:	P04626
WB Predicted band size:	138 kDa
WB Positive control:	HepG2 cells lysates
WB Recommended dilution:	500-1000