中文名稱：兔抗DPPA4多克隆抗體

英文名稱： Anti-DPPA4 rabbit polyclonal antibody

別名： developmental pluripotency associated 4; 2410091M23Rik

相關(guān)類別： 一抗

儲存： 冷凍（-20℃）

宿主： Rabbit

抗原： DPPA4

反應(yīng)種屬： Human

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

DPPA4

Immunogen:

Synthetic peptide of human DPPA4

Full name:

developmental pluripotency associated 4

Synonyms:

2410091M23Rik

SwissProt:

Q7L190

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human breast cancer and Human esophagus cancer

IHC Recommend dilution:

40-200

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兔抗DPPA4多克隆抗體

Background:	This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Applications:	ELISA, IHC
Name of antibody:	DPPA4
Immunogen:	Synthetic peptide of human DPPA4
Full name:	developmental pluripotency associated 4
Synonyms:	2410091M23Rik
SwissProt:	Q7L190
ELISA Recommended dilution:	5000-10000
IHC positive control:	Human breast cancer and Human esophagus cancer
IHC Recommend dilution:	40-200