中文名稱(chēng)：兔抗DNAJA1多克隆抗體

英文名稱(chēng)： Anti-DNAJA1 rabbit polyclonal antibody

別名： DJ-2; DjA1; HDJ2; HSDJ; HSJ2; HSPF4; NEDD7; hDJ-2

相關(guān)類(lèi)別： 一抗

儲(chǔ) 存： 冷凍（-20℃）

抗原： DNAJA1

宿主： Rabbit

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記物： Unconjugate

克隆類(lèi)型： rabbit polyclonal

技術(shù)規(guī)格

Background:

DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.

Applications:

ELISA, WB, IHC

Name of antibody:

DNAJA1

Immunogen:

Fusion protein of human DNAJA1

Full name:

DnaJ (Hsp40) homolog, subfamily A, member 1

Synonyms：

DJ-2; DjA1; HDJ2; HSDJ; HSJ2; HSPF4; NEDD7; hDJ-2

SwissProt:

P31689

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and human thyroid cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

45 kDa

WB Positive control:

HepG2, Raji, A431 and 231 cells

WB Recommended dilution:

500-2000

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兔抗DNAJA1多克隆抗體

Background:	DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.
Applications:	ELISA, WB, IHC
Name of antibody:	DNAJA1
Immunogen:	Fusion protein of human DNAJA1
Full name:	DnaJ (Hsp40) homolog, subfamily A, member 1
Synonyms：	DJ-2; DjA1; HDJ2; HSDJ; HSJ2; HSPF4; NEDD7; hDJ-2
SwissProt:	P31689
ELISA Recommended dilution:	2000-5000
IHC positive control:	Human colon cancer and human thyroid cancer
IHC Recommend dilution:	100-300
WB Predicted band size:	45 kDa
WB Positive control:	HepG2, Raji, A431 and 231 cells
WB Recommended dilution:	500-2000