購(gòu)物車(chē)
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021-54845833/15800441009
中文名稱(chēng)： 兔抗MDC1多克隆抗體
英文名稱(chēng)： Anti-MDC1 rabbit polyclonal antibody
別 名： NFBD1
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MDC1
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MDC1 |
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Immunogen: |
Synthetic peptide of human MDC1 |
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Full name: |
Mediator of DNA-damage checkpoint 1 |
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Synonyms： |
NFBD1 |
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SwissProt: |
Q14676 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
100-300 |
