中文名稱：兔抗DEAF1多克隆抗體

英文名稱： Anti-DEAF1 rabbit polyclonal antibody

別名： SPN; NUDR; ZMYND5

抗原： DEAF1

儲存： 冷凍（-20℃）

宿主： Rabbit

相關(guān)類別：一抗

反應種屬： Human

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Suppressin, also known as DEAF1 (deformed epidermal autoregulatory factor 1), SPN, NUDR (nuclear DEAF-1-related transcriptional regulator), or ZMYND5 (zinc finger MYND domain-containing protein 5), is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.

Applications:

ELISA, IHC

Name of antibody:

DEAF1

Immunogen:

Synthetic peptide of human DEAF1

Full name:

DEAF1 transcription factor

Synonyms:

SPN; NUDR; ZMYND5

SwissProt:

O75398

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

50-200

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ELISA試劑盒

PCR試劑盒

生化試劑盒

細胞系

細胞庫

基礎培養(yǎng)基

完全培養(yǎng)基

原代細胞

細胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

標準品

血清

形態(tài)病理檢測

分子病理

超微病理

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兔抗DEAF1多克隆抗體

Background:	Suppressin, also known as DEAF1 (deformed epidermal autoregulatory factor 1), SPN, NUDR (nuclear DEAF-1-related transcriptional regulator), or ZMYND5 (zinc finger MYND domain-containing protein 5), is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.
Applications:	ELISA, IHC
Name of antibody:	DEAF1
Immunogen:	Synthetic peptide of human DEAF1
Full name:	DEAF1 transcription factor
Synonyms:	SPN; NUDR; ZMYND5
SwissProt:	O75398
IHC positive control:	Human gastric cancer
IHC Recommend dilution:	50-200