中文名稱：兔抗DDIT4多克隆抗體

英文名稱： Anti-DDIT4 rabbit polyclonal antibody

別名： Dig2; REDD1; REDD-1

相關(guān)類別：一抗

儲存： 冷凍（-20℃）

抗原： DDIT4

宿主： Rabbit

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

REDD-1, also designated DNA-damage-inducible transcript 4, dig2 or RTP801, is thought to function in the regulation of reactive oxygen species (ROS). REDD-1 expression has also been linked to apoptosis, Ab toxicity and the pathogenesis of ischemic diseases. As an HIF-1-responsive gene, REDD-1 exhibits strong hypoxia-dependent upregulation in ischemic cells of neuronal origin. In response to stress due to DNA damage and glucocorticoid treatment, REDD-1 is upregulated at the transcriptional level. REDD-1 negatively regulates the mammalian target of Rapamycin (mTOR), a serine/threonine kinase often referred to as FRAP. It is crucial in the coupling of extra- and intracellular cues to FRAP regulation. The absence of REDD-1 is associated with the development of retinopathy, a major cause of blindness.

Applications:

ELISA, IHC

Name of antibody:

DDIT4

Immunogen:

Fusion protein of human DDIT4

Full name:

DNA-damage-inducible transcript 4

Synonyms：

Dig2; REDD1; REDD-1

SwissProt:

Q9NX09

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and human gastric cancer

IHC Recommend dilution:

50-200

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兔抗DDIT4多克隆抗體

Background:	REDD-1, also designated DNA-damage-inducible transcript 4, dig2 or RTP801, is thought to function in the regulation of reactive oxygen species (ROS). REDD-1 expression has also been linked to apoptosis, Ab toxicity and the pathogenesis of ischemic diseases. As an HIF-1-responsive gene, REDD-1 exhibits strong hypoxia-dependent upregulation in ischemic cells of neuronal origin. In response to stress due to DNA damage and glucocorticoid treatment, REDD-1 is upregulated at the transcriptional level. REDD-1 negatively regulates the mammalian target of Rapamycin (mTOR), a serine/threonine kinase often referred to as FRAP. It is crucial in the coupling of extra- and intracellular cues to FRAP regulation. The absence of REDD-1 is associated with the development of retinopathy, a major cause of blindness.
Applications:	ELISA, IHC
Name of antibody:	DDIT4
Immunogen:	Fusion protein of human DDIT4
Full name:	DNA-damage-inducible transcript 4
Synonyms：	Dig2; REDD1; REDD-1
SwissProt:	Q9NX09
ELISA Recommended dilution:	2000-5000
IHC positive control:	Human liver cancer and human gastric cancer
IHC Recommend dilution:	50-200