Name: SPATA17抗原（重組蛋白）
Brand: 通蔚生物

中文名稱(chēng)： SPATA17抗原（重組蛋白）

英文名稱(chēng)： SPATA17 Antigen (Recombinant Protein)

別名： IQCH, MSRG11, MSRG-11, RP11-144C20.1

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別：抗原

概述

Fusion protein corresponding to C terminal 300 amino acids of human SPATA17

技術(shù)規(guī)格

Full name:	spermatogenesis associated 17
Synonyms:	IQCH, MSRG11, MSRG-11, RP11-144C20.1
Swissprot:	Q96L03
Gene Accession:	BC014608
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Spata17 gene, which called MSRG11, by digital differential display of ESTs found only in testis. The deduced 292-amino acid protein was considered to be a member of the family of calmodulin (CaM)-binding proteins because it contained 3 short CaM-binding motifs containing conserved ile and gln residues (IQ motif). Spata17 protein was most abundant in the cytoplasm of round spermatids and elongating spermatids within seminiferous tubules of the adult testis. Expression gradually decreased in the manipulated testis of animals that underwent experimental unilateral cryptorchidism. Transient transfection experiments with a Spata17 expression construct in cultured spermatogonia GC-1 cells indicated that Spata17 accelerated apoptosis in a dose-dependent manner.

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