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021-54845833/15800441009
中文名稱： 兔抗MANF多克隆抗體
英文名稱： Anti-MANF rabbit polyclonal antibody
別 名： ARP; ARMET
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MANF
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
Background:
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Applications:
ELISA, IHC
Name of antibody:
MANF
Immunogen:
Synthetic peptide of human MANF
Full name:
mesencephalic astrocyte-derived neurotrophic factor
Synonyms：
ARP; ARMET
SwissProt:
P55145
ELISA Recommended dilution:
2000-10000
IHC positive control:
Human thyroid cancer and Human colon cancer
IHC Recommend dilution:
100-300
