Name: AUP1 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：AUP1 抗原（重組蛋白）

英文名稱： AUP1 Antigen (Recombinant Protein)

別名： ancient ubiquitous protein 1

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to C terminal 250 amino acids of human AUP1

技術(shù)規(guī)格：

Full name:	ancient ubiquitous protein 1
Swissprot:	Q9Y679
Gene Accession:	BC033646
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.

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