Name: ARHGEF10抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：ARHGEF10抗原（重組蛋白）

英文名稱： ARHGEF10 Antigen (Recombinant Protein)

別名： GEF10

儲存： 冷凍（-20℃）

相關類別： 抗原

概述：

Fusion protein corresponding to C terminal 300 amino acids of human ARHGEF10

技術規格：

Full name:	Rho guanine nucleotide exchange factor (GEF) 10
Synonyms:	GEF10
Swissprot:	O15013
Gene Accession:	BC036809
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. ARHGEF10 (rho guanine nucleotide exchange factor 10), also known as GEF10 or KIAA0294, is a 1,369 amino acid protein that contains one DBL-homology domain and is thought to play a role in myelination of peripheral nerves, specifically during development. ARHGEF10 is expressed as four alternatively spliced isoforms that are present at low levels in ovary, lung, testis and kidney, with considerably higher expression in the central and peripheral nervous systems.

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