購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： EIF2AK3抗原（重組蛋白）
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Full name: |
eukaryotic translation initiation factor 2 alpha kinase 3 |
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Synonyms: |
PEK; WRS; PERK |
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Swissprot: |
Q9NZJ5 |
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Gene Accession: |
BC126354 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
