Name: CHRNA4抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： CHRNA4抗原（重組蛋白）

英文名稱： CHRNA4 Antigen (Recombinant Protein)

別名： EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 331-600 amino acids of human CHRNA4

技術(shù)規(guī)格

Full name:	cholinergic receptor, nicotinic, alpha 4 (neuronal)
Synonyms:	EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4
Swissprot:	P43681
Gene Accession:	BC096290
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1.

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