Name: EDARADD抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： EDARADD抗原（重組蛋白）

英文名稱： EDARADD Antigen (Recombinant Protein)

別名： ED3; EDA3; ECTD11A; ECTD11B

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Full length fusion protein

技術(shù)規(guī)格

Full name:	EDAR-associated death domain
Synonyms:	ED3; EDA3; ECTD11A; ECTD11B
Swissprot:	Q8WWZ3
Gene Accession:	BC128082
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

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