中文名稱：兔抗CRK多克隆抗體

英文名稱： Anti-CRK rabbit polyclonal antibody

別名： p38; CRKII

相關(guān)類別：一抗

抗原： CRK

儲存： 冷凍（-20℃）

宿主： Rabbit

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

Applications:

ELISA, IHC

Name of antibody:

CRK

Immunogen:

Fusion protein of human CRK

Full name:

v-crk avian sarcoma virus CT10 oncogene homolog

Synonyms：

p38; CRKII

SwissProt:

P46108

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer

IHC Recommend dilution:

50-200

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兔抗CRK多克隆抗體

Background:	This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Applications:	ELISA, IHC
Name of antibody:	CRK
Immunogen:	Fusion protein of human CRK
Full name:	v-crk avian sarcoma virus CT10 oncogene homolog
Synonyms：	p38; CRKII
SwissProt:	P46108
ELISA Recommended dilution:	2000-5000
IHC positive control:	Human colon cancer
IHC Recommend dilution:	50-200