購(gòu)物車
幫助
021-54845833/15800441009
標(biāo) 記 物： Unconjugate
技術(shù)規(guī)格
Background:
This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.
Applications:
WB, IHC, IF
Name of antibody:
TBL1XR1
Immunogen:
Fusion protein of human TBL1XR1
Full name:
transducin beta like 1 X-linked receptor 1
Synonyms:
C21; DC42; IRA1; MRD41; TBLR1
SwissProt:
Q9BZK7
IHC positive control:
Human breast cancer
IHC Recommend dilution:
500-1000
WB Predicted band size:
56 kDa
WB Positive control:
Mouse brain tissue, Mouse heart tissue and K562 cell lysates
WB Recommended dilution:
1000-5000
IF positive control:
Hela cells
IF Recommend dilution:
100-200
